Braftovi (encorafenib) 75 mg, 168 tablets, France

Indication

Encorafenib is indicated in combination with binimetinib for the treatment of adult patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation and metastatic non-small cell lung cancer (NSCLC) with a BRAF V600E mutation. It is also indicated in combination with cetuximab for the treatment of adult patients with metastatic colorectal cancer with a BRAF V600E mutation.5

It is also indicated under accelerated approval in combination with cetuximab and mFOLFOX6 (oxaliplatin, leucovorin, fluorouracil), for the treatment of patients with metastatic colorectal cancer (mCRC) with a BRAF V600E mutation, as detected by an FDA-approved test. 6